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The injectable versions of semaglutide for reducing body weight are taken once a week, on the same day of the week every week

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It also states that, if needed for weight management in adult patients with obesity, the dose can be increased to 7.2 mg once weekly after a minimum of four weeks on 2.4 mg, using three 2.4 mg injections, with dose escalation delayed or reduced if significant gastrointestinal symptoms occur

The SELECT trial, comprising 17,604 patients, was conducted at 804 sites across 41 countries, focused on patients aged 45 or older with a BMI of at least 27 kg/m and preexisting CVD but no history of diabetes

To ensure the objectivity and reproducibility of our quality assessment process, each study was independently evaluated by two researchers

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